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  • Small RNAs from 11 Drosophila species

    Authors
    Mohammed, Jaaved
    Flynt, Alex S
    Lai, Eric C
    Description

    Summary from the GEO: "Annotation of small RNAs from 11 Drosophila species for the purpose of non-coding RNA annotation and comparative genomics assessment." Overall design from the GEO: "Small RNA samples from 11 Drosophila species." Abstract Summary: "To assess miRNA evolution across the Drosophila genus, we analyzed several billion small RNA reads across 12 fruit fly species. These data permit...

    Subject
    Drosophila
    Genomics
    RNA, Small Untranslated
    RNA, Untranslated
    Access Rights
    Free to All
  • Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts

    Authors
    Vedanayagam, Jeffrey
    Lin, Ching-Jung
    Papareddy, Ranjith
    Nodine, Michael
    3 more author(s)...
    Description

    Summary from GEO: "Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpRNA) loci generate endo-siRNAs that suppress evolutionary novel, X-linked, meiotic...

    Subject
    Gene Expression
    RNA Interference
    RNA-Seq
    RNA, Small Interfering
    Spermatogenesis
    Access Rights
    Free to All